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A Fibre Concept with proven Prebiotic Benefits

The gut microbiota plays a far broader role than digestion alone, influencing immune modulation, barrier integrity and overall patient well-being. In patients receiving enteral nutrition, maintaining this ecosystem requires deliberate nutritional support beyond standard formulations.2-4

Vital Gut* is the fibre concept underpinning the fibre-containing Fresubin tube feed range, combining soluble fibres, inulin and wheat dextrin, with insoluble cellulose in proportions designed to address multiple aspects of gut function simultaneously.1

Feeds Gut Microbiota

Vital Gut fibre acts as a key nutrient for the gut microbiota. As beneficial bacteria multiply, they ferment the soluble fibre portion, resulting in a significant increase in short-chain fatty acid (SCFA) production, including butyrate, acetate, and propionate, which are vital for colon health.1

Microbiota graphic

Maintains Gut Barrier

Vital Gut enhances immune function by increasing the anti-inflammatory cytokine IL-10, as SCFAs provide energy to colonocytes, regulate inflammation, and help maintain the gut barrier.1

Microbe graphic

Lowers Fecal pH

Vital Gut significantly lowers faecal pH through increased SCFA production, creating an unfavourable environment for harmful pathogens.1

Low pH graphic

Matching Protein Kinetics to Individual Patient Requirements

Gut function is frequently compromised in patients receiving enteral nutrition, whether due to illness, immobility, medication, or the nature of the feeding regimen itself. Vital Gut is designed to support gut health across diverse patient groups.

ESPEN guidelines recommend fibre-containing enteral nutrition, reinforcing the role of a structured fibre approach as part of routine clinical nutrition practice.3,4

Two older adults enjoy time outdoors while their nutritional needs are supported by Fresubin Vital Gut, designed to support digestive health.

Consistent Quality Across the Fresubin Fibre-Containing Range

Vital Gut fibre blends are incorporated across the Fresubin fibre-containing tube feed portfolio, allowing clinicians to select the appropriate energy density and protein level for each patient whilst maintaining a consistent approach to gut health support throughout the care pathway.

Fresubin products containing VITAL GUT:
• Fresubin ORIGINAL FIBRE
• Fresubin ENERGY FIBRE
• Fresubin HP ENERGY FIBRE
• Fresubin 2 KCAL FIBRE / 2 KCAL HP FIBRE
• Frebini ENERGY FIBRE
• Frebini ORIGINAL FIBRE
• Fresubin MEGAREAL FIBRE

Fresubin tube feeds containing Vital Gut include Fresubin ORIGINAL FIBRE, ENERGY FIBRE, HP ENERGY FIBRE, 2 KCAL HP FIBRE and MEGAREAL FIBRE, providing a consistent fibre concept across the range.

Tube Feed factsheets can be downloaded here:

VitalGUT

Filename
Fresubin_VitalGUT_B_HCP_Jul2025.pdf
Size
5 MB
Format
pdf
*Fresubin products are food for special medical purposes, to be used under medical supervision. Vital Gut is a supportive formulation concept and does not constitute a therapeutic claim. For Healthcare Professionals only.

 

References:

1 Ghyselinck J et al. Front Nutr. 2026;13:1749272.
2 McClave SA et al.  Nutr Clin Pract. 2024;39(3):546-556.
3 Wunderle C et al. Clin Nutr. 2023;42(9):1545-1568
4 Volkert D et al. Clin Nutr. 2023;42(9):1545-1568.

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